
Associate Professor
Neurology
+1 415 476-3861
Maria Luisa Mandelli leads the neuroimaging research within the language team of the Memory and Aging Center. Her research focuses on neuroanatomical changes caused by language, and other neurodegenerative disorders. She has been working on brain magnetic resonance imaging for the past 10 years, with the goal of better understanding of how the brain develops, changes over time, and how it makes us who we are.
She completed a PhD in Biomedical Engineering in Italy at the Politecnico di Milano in collaboration with Neurological Institute C. Besta. Maria Luisa joined UCSF in 2010, specializing in brain imaging processing.
Publications
Verbal short-term memory in developmental dyslexia: The role of the temporoparietal area.
Brain and language
Anatomical and behavioural correlates of auditory perception in developmental dyslexia.
Brain : a journal of neurology
A semantic strength and neural correlates in developmental dyslexia.
Frontiers in psychology
Network changes associated with right anterior temporal lobe atrophy: insight into unique symptoms.
medRxiv : the preprint server for health sciences
Non-right-handedness, male sex, and regional, network-specific, ventral occipito-temporal anomalous lateralization in adults with a history of reading disability.
Cortex; a journal devoted to the study of the nervous system and behavior
Digital language markers distinguish frontal from right anterior temporal lobe atrophy in frontotemporal dementia.
medRxiv : the preprint server for health sciences
Boundary-based registration improves sensitivity for detecting hypoperfusion in sporadic frontotemporal lobar degeneration.
Frontiers in neurology
Anatomical and behavioral correlates of auditory perception in developmental dyslexia.
bioRxiv : the preprint server for biology
Perceptual and semantic deficits in face recognition in semantic dementia.
medRxiv : the preprint server for health sciences
Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum.
Brain : a journal of neurology
Parallel Encoding of Speech in Human Frontal and Temporal Lobes.
bioRxiv : the preprint server for biology
Discriminating nonfluent/agrammatic and logopenic PPA variants with automatically extracted morphosyntactic measures from connected speech.
Cortex; a journal devoted to the study of the nervous system and behavior
Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum.
Brain : a journal of neurology
Functional network collapse in neurodegenerative disease.
bioRxiv : the preprint server for biology
Assessing processing speed and its neural correlates in the three variants of primary progressive aphasia with a non-verbal tablet-based task.
Cortex; a journal devoted to the study of the nervous system and behavior
Network connectivity alterations across the MAPT mutation clinical spectrum.
Annals of neurology
Distinct neurophysiology during nonword repetition in logopenic and non-fluent variants of primary progressive aphasia.
Human brain mapping
Network anatomy in logopenic variant of primary progressive aphasia.
Human brain mapping
Network anatomy in logopenic variant of primary progressive aphasia.
medRxiv : the preprint server for health sciences
Spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia.
Brain communications
Correction: Cortical microstructure in primary progressive aphasia: a multicenter study.
Alzheimer's research & therapy
Baseline structural imaging correlates of treatment outcomes in semantic variant primary progressive aphasia.
Cortex; a journal devoted to the study of the nervous system and behavior
Visual and social differences in dyslexia: deep phenotyping of four cases with spared phonology.
Neurocase
Right temporal lobe and socioemotional semantics: semantic behavioural variant frontotemporal dementia.
Brain : a journal of neurology
Comparison between inferior frontal gyrus intrinsic connectivity network and verb-generation task fMRI network for presurgical language mapping in healthy controls and in glioma patients.
Brain imaging and behavior
Probabilistic Decision-Making in Children With Dyslexia.
Frontiers in neuroscience
Default Mode Network quantitative diffusion and resting-state functional magnetic resonance imaging correlates in sporadic Creutzfeldt-Jakob disease.
Human brain mapping
Right uncinate fasciculus supports socioemotional sensitivity in health and neurodegenerative disease.
NeuroImage. Clinical
Cortical microstructure in primary progressive aphasia: a multicenter study.
Alzheimer's research & therapy
Functional and morphological correlates of developmental dyslexia: A multimodal investigation of the ventral occipitotemporal cortex.
Journal of neuroimaging : official journal of the American Society of Neuroimaging
Cortically constrained shape recognition: Automated white matter tract segmentation validated in the pediatric brain.
Journal of neuroimaging : official journal of the American Society of Neuroimaging
Enhanced visceromotor emotional reactivity in dyslexia and its relation to salience network connectivity.
Cortex; a journal devoted to the study of the nervous system and behavior
Regional and hemispheric susceptibility of the temporal lobe to FTLD-TDP type C pathology.
NeuroImage. Clinical
MRI Measurement of Upper Cervical Spinal Cord Cross-Sectional Area in Children.
Journal of neuroimaging : official journal of the American Society of Neuroimaging
Task-free functional language networks: reproducibility and clinical application.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia.
Brain communications
Neurocognitive basis of repetition deficits in primary progressive aphasia.
Brain and language
Differential intrinsic functional connectivity changes in semantic variant primary progressive aphasia.
NeuroImage. Clinical
"Looks familiar, but I do not know who she is": The role of the anterior right temporal lobe in famous face recognition.
Cortex; a journal devoted to the study of the nervous system and behavior
Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates.
Amyotrophic lateral sclerosis & frontotemporal degeneration
Altered topology of the functional speech production network in non-fluent/agrammatic variant of PPA.
Cortex; a journal devoted to the study of the nervous system and behavior
Prevalence of Mathematical and Visuospatial Learning Disabilities in Patients With Posterior Cortical Atrophy.
JAMA neurology
Retraining speech production and fluency in non-fluent/agrammatic primary progressive aphasia.
Brain : a journal of neurology
Abnormal age-related cortical folding and neurite morphology in children with developmental dyslexia.
NeuroImage. Clinical
Distinct spatiotemporal patterns of neuronal functional connectivity in primary progressive aphasia variants.
Brain : a journal of neurology
Early changes in brain structure correlate with language outcomes in children with neonatal encephalopathy.
NeuroImage. Clinical
Typical and atypical pathology in primary progressive aphasia variants.
Annals of neurology
Focal temporal pole atrophy and network degeneration in semantic variant primary progressive aphasia.
Brain : a journal of neurology
Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers.
NeuroImage. Clinical
Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia.
Brain : a journal of neurology
Reading words and other people: A comparison of exception word, familiar face and affect processing in the left and right temporal variants of primary progressive aphasia.
Cortex; a journal devoted to the study of the nervous system and behavior
Structural connectivity of the human anterior temporal lobe: A diffusion magnetic resonance imaging study.
Human brain mapping
Two insular regions are differentially involved in behavioral variant FTD and nonfluent/agrammatic variant PPA.
Cortex; a journal devoted to the study of the nervous system and behavior
Phonological Processing in Primary Progressive Aphasia.
Journal of cognitive neuroscience
White matter involvement in sporadic Creutzfeldt-Jakob disease.
Brain : a journal of neurology
Frontal white matter tracts sustaining speech production in primary progressive aphasia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Quantifying accuracy and precision of diffusion MR tractography of the corticospinal tract in brain tumors.
Journal of neurosurgery
Frontal cortex BOLD signal changes in premanifest Huntington disease: a possible fMRI biomarker.
Neurology
Application of quantitative DTI metrics in sporadic CJD.
NeuroImage. Clinical
In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology.
Neurology
What role does the anterior temporal lobe play in sentence-level processing? Neural correlates of syntactic processing in semantic variant primary progressive aphasia.
Journal of cognitive neuroscience
Handedness and language learning disability differentially distribute in progressive aphasia variants.
Brain : a journal of neurology
Quantifying diffusion MRI tractography of the corticospinal tract in brain tumors with deterministic and probabilistic methods.
NeuroImage. Clinical
Neural stem cell engraftment and myelination in the human brain.
Science translational medicine
Functional connectivity during resting-state functional MR imaging: study of the correspondence between independent component analysis and region-of-interest-based methods.
AJNR. American journal of neuroradiology
Pain processing in medication overuse headache: a functional magnetic resonance imaging (fMRI) study.
Pain medicine (Malden, Mass.)
Decreased diffusivity in the caudate nucleus of presymptomatic huntington disease gene carriers: which explanation?
AJNR. American journal of neuroradiology
Diffusion tensor imaging shows different topographic involvement of the thalamus in progressive supranuclear palsy and corticobasal degeneration.
AJNR. American journal of neuroradiology
Functional-MRI evaluation of pain processing in chronic migraine with medication overuse.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease.
Brain : a journal of neurology
Elevating tensor rank increases anisotropy in brain areas associated with intra-voxel orientational heterogeneity (IVOH): a generalised DTI (GDTI) study.
NMR in biomedicine
Diffusion tensor imaging of spinocerebellar ataxias types 1 and 2.
AJNR. American journal of neuroradiology
Dural sinus thrombosis in spontaneous intracranial hypotension: Hypotheses on possible mechanisms.
Journal of neurology
Epidemiology and risk factors of pneumonia in critically ill patients. Intensive Care Unit Group for Infection Control.
European journal of epidemiology
Pharmacokinetics and tolerance of a new penem antibiotic, FCE 22101, in healthy volunteers after a single intravenous dose.
European journal of clinical pharmacology